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Recent advancements in crop biotechnology are transforming agriculture by addressing key challenges such as food security, environmental sustainability, and climate resilience. This article explores the latest breakthroughs in crop biotechnology, including gene-editing technologies like CRISPR-Cas9, genome-wide association studies (GWAS), synthetic biology, and microbiome engineering. It also highlights the role of advanced breeding techniques and the development of climate-resilient crops in enhancing productivity and sustainability. By integrating these innovations, crop biotechnology is paving the way for more efficient, resilient, and sustainable agricultural practices, crucial for meeting the demands of a growing global population.